6NBH

Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein

Summary for 6NBH

EMDB information0411
DescriptorParathyroid hormone/parathyroid hormone-related peptide receptor, Long-acting parathyroid hormone analog, Gs protein alpha subunit, ... (8 entities in total)
Functional Keywordsparathyroid hormone receptor, gpcr, class b gpcr, gpcr-g protein complex, signaling protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains6
Total molecular weight165860.57
Authors
Primary citation
Zhao, L.H.,Ma, S.,Sutkeviciute, I.,Shen, D.D.,Zhou, X.E.,de Waal, P.W.,Li, C.Y.,Kang, Y.,Clark, L.J.,Jean-Alphonse, F.G.,White, A.D.,Yang, D.,Dai, A.,Cai, X.,Chen, J.,Li, C.,Jiang, Y.,Watanabe, T.,Gardella, T.J.,Melcher, K.,Wang, M.W.,Vilardaga, J.P.,Xu, H.E.,Zhang, Y.
Structure and dynamics of the active human parathyroid hormone receptor-1.
Science, 364:148-153, 2019
PubMed: 30975883 (PDB entries with the same primary citation)
DOI: 10.1126/science.aav7942
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers200MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 6nbh
no rotation
Molmil generated image of 6nbh
rotated about x axis by 90°
Molmil generated image of 6nbh
rotated about y axis by 90°