6N8W

Structure of Unliganded Hsp90-Beta N-Terminal Domain

Summary for 6N8W

Entry DOI	10.2210/pdb6n8w/pdb
Descriptor	Heat shock protein HSP 90-beta, GLYCEROL (3 entities in total)
Functional Keywords	heat-shock, hsp90, cytosolic, chaperone
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	115525.19
Authors	Huck, J.D.,Que, N.L.S.,Gewirth, D.T. (deposition date: 2018-11-30, release date: 2019-07-03, Last modification date: 2024-03-13)
Primary citation	Huck, J.D.,Que, N.L.S.,Sharma, S.,Taldone, T.,Chiosis, G.,Gewirth, D.T. Structures of Hsp90 alpha and Hsp90 beta bound to a purine-scaffold inhibitor reveal an exploitable residue for drug selectivity. Proteins, 87:869-877, 2019 Cited by PubMed: 31141217 DOI: 10.1002/prot.25750 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.0922814017 Å)

Structure validation