Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006457 | biological_process | protein folding |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0051082 | molecular_function | unfolded protein binding |
| A | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006457 | biological_process | protein folding |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0051082 | molecular_function | unfolded protein binding |
| B | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006457 | biological_process | protein folding |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0051082 | molecular_function | unfolded protein binding |
| C | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006457 | biological_process | protein folding |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0051082 | molecular_function | unfolded protein binding |
| D | 0140662 | molecular_function | ATP-dependent protein folding chaperone |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | ILE105 |
| A | SER108 |
| B | GLU13 |
| B | PHE15 |
| B | LYS95 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | SER34 |
| A | GLU191 |
| A | GOL303 |
| D | THR190 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 303 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | LYS53 |
| A | MET93 |
| A | THR179 |
| A | GOL307 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 305 |
| Chain | Residue |
| A | GLU13 |
| A | PHE15 |
| A | LYS95 |
| B | ILE105 |
| B | SER108 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 306 |
| Chain | Residue |
| A | HIS6 |
| A | GLY8 |
| B | ALA112 |
| C | GLN207 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 307 |
| Chain | Residue |
| A | ASN46 |
| A | MET93 |
| A | THR179 |
| A | GOL304 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue GOL A 308 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 301 |
| Chain | Residue |
| B | GLU9 |
| D | ASP52 |
| D | ARG55 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue GOL B 302 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 303 |
| Chain | Residue |
| A | GLN23 |
| B | GLU141 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 304 |
| Chain | Residue |
| B | ASN78 |
| B | GLU81 |
| B | THR83 |
| B | THR85 |
| B | LYS180 |
| B | GOL305 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 305 |
| Chain | Residue |
| B | ILE146 |
| B | ASP170 |
| B | GLY172 |
| B | LYS180 |
| B | ILE182 |
| B | GOL304 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 306 |
| Chain | Residue |
| B | ASN46 |
| B | LEU102 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 308 |
| Chain | Residue |
| B | ASP49 |
| B | GLY127 |
| B | GLY130 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 309 |
| Chain | Residue |
| B | GLU191 |
| B | GLU194 |
| B | GOL310 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 310 |
| Chain | Residue |
| B | THR190 |
| B | GLU191 |
| B | GLU194 |
| B | GOL309 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| B | GLN207 |
| C | GLU115 |
| D | HIS7 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 302 |
| Chain | Residue |
| B | ARG41 |
| B | SER124 |
| C | ARG41 |
| C | SER124 |
| C | MET125 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 303 |
| Chain | Residue |
| C | ASP49 |
| C | GLY130 |
| C | GOL310 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 304 |
| Chain | Residue |
| C | ALA50 |
| C | MET93 |
| C | THR179 |
| C | GOL310 |
| C | HOH404 |
| site_id | AE4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 306 |
| Chain | Residue |
| A | ARG55 |
| A | GLY210 |
| A | TYR211 |
| A | PRO212 |
| C | GLU9 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 307 |
| Chain | Residue |
| A | GLU153 |
| C | LEU65 |
| C | LYS69 |
| C | LEU71 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 308 |
| Chain | Residue |
| B | PHE208 |
| C | GLY109 |
| C | PHE129 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 309 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 310 |
| Chain | Residue |
| C | ASN101 |
| C | ALA106 |
| C | GOL303 |
| C | GOL304 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 311 |
| Chain | Residue |
| B | GLN80 |
| C | PRO79 |
| C | GLN80 |
| C | GLU218 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 312 |
| Chain | Residue |
| C | GLY120 |
| D | GLY162 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL D 301 |
| Chain | Residue |
| A | GLY127 |
| A | GLY130 |
| A | SER45 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL D 302 |
| Chain | Residue |
| D | ASN101 |
| D | LEU102 |
| D | ALA106 |
| D | GLY130 |
| site_id | AF4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL D 303 |
| Chain | Residue |
| A | PHE208 |
| D | SER108 |
| D | GLY109 |
Functional Information from PROSITE/UniProt
| site_id | PS00298 |
| Number of Residues | 10 |
| Details | HSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE |
| Chain | Residue | Details |
| A | TYR33-GLU42 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 848 |
| Details | Region: {"description":"Interaction with BIRC2","evidences":[{"source":"PubMed","id":"25486457","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Site: {"description":"Cleaved under oxidative stress","evidences":[{"source":"PubMed","id":"22848402","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P11499","evidenceCode":"ECO:0000250"}]} |
