6N4Y
Metabotropic Glutamate Receptor 5 Extracellular Domain with Nb43
Summary for 6N4Y
Entry DOI | 10.2210/pdb6n4y/pdb |
Descriptor | Metabotropic glutamate receptor 5, Nanobody 43, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | cell surface receptor nanobody, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 327595.49 |
Authors | Koehl, A.,Hu, H.,Feng, D.,Sun, B.,Chu, M.,Weis, W.I.,Mathiesen, J.M.,Skiniotis, G.,Kobilka, B.K. (deposition date: 2018-11-20, release date: 2019-01-23, Last modification date: 2023-10-11) |
Primary citation | Koehl, A.,Hu, H.,Feng, D.,Sun, B.,Zhang, Y.,Robertson, M.J.,Chu, M.,Kobilka, T.S.,Laermans, T.,Steyaert, J.,Tarrasch, J.,Dutta, S.,Fonseca, R.,Weis, W.I.,Mathiesen, J.M.,Skiniotis, G.,Kobilka, B.K. Structural insights into the activation of metabotropic glutamate receptors. Nature, 566:79-84, 2019 Cited by PubMed: 30675062DOI: 10.1038/s41586-019-0881-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.262 Å) |
Structure validation
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