6MW7

Crystal structure of ATPase module of SMCHD1 bound to ATP

Summary for 6MW7

• Entry DOI: 10.2210/pdb6mw7/pdb
• Descriptor: Structural maintenance of chromosomes flexible hinge domain-containing protein 1, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: ghkl-atpase, epigenetic repressor, bosma arhinia microphthalmia, fascioscapulohumeral muscular dystrophy type 2, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 263231.01

Authors

Pedersen, L.C.,Inoue, K.,Kim, S.,Perera, L.,Shaw, N.D. (deposition date: 2018-10-29, release date: 2019-09-11, Last modification date: 2019-12-18)

• Primary citation: Pedersen, L.C.,Inoue, K.,Kim, S.,Perera, L.,Shaw, N.D.; A ubiquitin-like domain is required for stabilizing the N-terminal ATPase module of human SMCHD1.; Commun Biol, 2:255-255, 2019; PubMed: 31312724; DOI: 10.1038/s42003-019-0499-y

Experimental method

X-RAY DIFFRACTION (2.194 Å)