6MW7
Crystal structure of ATPase module of SMCHD1 bound to ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | polymer | 562 | 65246.5 | 4 | UniProt (A6NHR9) Pfam (PF13589) Pfam (PF22899) | Homo sapiens (Human) | SMC hinge domain-containing protein 1 |
| 2 | E, G, I, M (A, B, C, D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 3 | F, H, K, N (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | J (C) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | L (C) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 927 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 24 - 580 (UniProt: A6NHR9)
| PDB | External Database | Details |
|---|---|---|
| Gly 19 | - | expression tag |
| Ser 20 | - | expression tag |
| Ala 21 | - | expression tag |
| Ala 22 | - | expression tag |
| Ala 23 | - | expression tag |
| Ala 147 | Glu 147 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 260986.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2245.0 | |
| All* | Total formula weight | 263231.0 |
