6MVY

NavAb voltage-gated sodium channel, residues 1-226, crystallized in the presence of Class 1B Anti-arrhythmic drug Lidocaine

Summary for 6MVY

Entry DOI	10.2210/pdb6mvy/pdb
Related	6MVV 6MVW 6MVX
Descriptor	Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, SULFATE ION, ... (4 entities in total)
Functional Keywords	ion channel voltage-gated sodium channel, membrane protein
Biological source	Arcobacter butzleri (strain RM4018)
Total number of polymer chains	2
Total formula weight	62028.85
Authors	Lenaeus, M.J.,Catterall, W.A. (deposition date: 2018-10-28, release date: 2018-12-05, Last modification date: 2023-10-11)
Primary citation	Gamal El-Din, T.M.,Lenaeus, M.J.,Zheng, N.,Catterall, W.A. Fenestrations control resting-state block of a voltage-gated sodium channel. Proc. Natl. Acad. Sci. U.S.A., 115:13111-13116, 2018 Cited by PubMed: 30518562 DOI: 10.1073/pnas.1814928115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.002 Å)

Structure validation