6MVX
NavAb Voltage-gated Sodium Channel, I217C, in Complex with Class 1C Anti-arrhythmic Flecainide
Summary for 6MVX
| Entry DOI | 10.2210/pdb6mvx/pdb |
| Related | 6MVV 6MVW |
| Descriptor | Ion transport protein, PHOSPHATE ION, Flecainide (3 entities in total) |
| Functional Keywords | ion channel voltage-gated sodium channel, membrane protein |
| Biological source | Arcobacter butzleri (strain RM4018) |
| Total number of polymer chains | 4 |
| Total formula weight | 133784.43 |
| Authors | Lenaeus, M.J.,Catterall, W.A. (deposition date: 2018-10-28, release date: 2018-12-05, Last modification date: 2023-10-11) |
| Primary citation | Gamal El-Din, T.M.,Lenaeus, M.J.,Zheng, N.,Catterall, W.A. Fenestrations control resting-state block of a voltage-gated sodium channel. Proc. Natl. Acad. Sci. U.S.A., 115:13111-13116, 2018 Cited by PubMed: 30518562DOI: 10.1073/pnas.1814928115 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.455 Å) |
Structure validation
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