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6MVX

NavAb Voltage-gated Sodium Channel, I217C, in Complex with Class 1C Anti-arrhythmic Flecainide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DIon transport proteinpolymer28533105.14UniProt (A8EVM5)
Pfam (PF00520)
In PDB
Arcobacter butzleri (strain RM4018)
2A, B, C, DPHOSPHATE IONnon-polymer95.010Chemie (PO4)
3AFlecainidenon-polymer414.31Chemie (K4D)
Sequence modifications
A, B, C, D: 1001 - 1267 (UniProt: A8EVM5)
PDBExternal DatabaseDetails
Met 983-initiating methionine
Asp 984-expression tag
Tyr 985-expression tag
Lys 986-expression tag
Asp 987-expression tag
Asp 988-expression tag
Asp 989-expression tag
Asp 990-expression tag
Lys 991-expression tag
Gly 992-expression tag
Ser 993-expression tag
Leu 994-expression tag
Val 995-expression tag
Pro 996-expression tag
Arg 997-expression tag
Gly 998-expression tag
Ser 999-expression tag
His 1000-expression tag
Cys 1217Ile 217engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight132420.4
Non-Polymers*Number of molecules11
Total formula weight1364.1
All*Total formula weight133784.4
*Water molecules are not included.

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PDB entries from 2024-05-29

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