6MSN
Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with inhibitor thiomalate
Summary for 6MSN
Entry DOI | 10.2210/pdb6msn/pdb |
Descriptor | fumarate hydratase, IRON/SULFUR CLUSTER, (2S)-2-sulfanylbutanedioic acid, ... (4 entities in total) |
Functional Keywords | inhibitor, cytosolic, fumarate hydratase, lyase |
Biological source | Leishmania major |
Total number of polymer chains | 2 |
Total formula weight | 134030.52 |
Authors | Feliciano, P.R.,Drennan, C.L.,Nonato, M.C. (deposition date: 2018-10-17, release date: 2019-01-30, Last modification date: 2023-10-11) |
Primary citation | Feliciano, P.R.,Drennan, C.L.,Nonato, M.C. Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate. ACS Chem. Biol., 14:266-275, 2019 Cited by PubMed: 30645090DOI: 10.1021/acschembio.8b00972 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.591 Å) |
Structure validation
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