6MSN

Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with inhibitor thiomalate

6MSN の概要

• エントリーDOI: 10.2210/pdb6msn/pdb
• 分子名称: fumarate hydratase, IRON/SULFUR CLUSTER, (2S)-2-sulfanylbutanedioic acid, ... (4 entities in total)
• 機能のキーワード: inhibitor, cytosolic, fumarate hydratase, lyase
• 由来する生物種: Leishmania major
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 134030.52

構造登録者

Feliciano, P.R.,Drennan, C.L.,Nonato, M.C. (登録日: 2018-10-17, 公開日: 2019-01-30, 最終更新日: 2023-10-11)

• 主引用文献: Feliciano, P.R.,Drennan, C.L.,Nonato, M.C.; Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.; ACS Chem. Biol., 14:266-275, 2019; PubMed: 30645090; DOI: 10.1021/acschembio.8b00972

実験手法

X-RAY DIFFRACTION (1.591 Å)