6MSN

Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with inhibitor thiomalate

6MSN の概要

分子名称fumarate hydratase, IRON/SULFUR CLUSTER, (2S)-2-sulfanylbutanedioic acid, ... (4 entities in total)
機能のキーワードinhibitor, cytosolic, fumarate hydratase, lyase
由来する生物種Leishmania major
ポリマー鎖数2
分子量合計134030.52
構造登録者
Feliciano, P.R.,Drennan, C.L.,Nonato, M.C. (登録日: 2018-10-17, 公開日: 2019-01-30, 最終更新日: 2019-02-27)
主引用文献
Feliciano, P.R.,Drennan, C.L.,Nonato, M.C.
Crystal Structures of Fumarate Hydratases from Leishmania major in a Complex with Inhibitor 2-Thiomalate.
ACS Chem. Biol., 14:266-275, 2019
PubMed: 30645090 (主引用文献が同じPDBエントリー)
DOI: 10.1021/acschembio.8b00972
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.591 Å)
?

構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.17010 1.2% 1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード

他の静止画像(非対称単位)

Molmil generated image of 6msn
回転なし
Molmil generated image of 6msn
x軸(左右方向)周りに90°回転
Molmil generated image of 6msn
y軸(上下方向)周りに90°回転