6MR4

Crystal structure of the Sth1 bromodomain from S.cerevisiae

Summary for 6MR4

Entry DOI	10.2210/pdb6mr4/pdb
Descriptor	Nuclear protein STH1/NPS1 (2 entities in total)
Functional Keywords	bromodomain, gene expression, chromatin structure, acetylated-lysine histone binding, gene regulation
Biological source	Saccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains	6
Total formula weight	80117.95
Authors	Seo, H.S.,Hashimoto, H.,Krolak, A.,Debler, E.W.,Blus, B.J. (deposition date: 2018-10-11, release date: 2019-07-24, Last modification date: 2023-10-11)
Primary citation	Blus, B.J.,Hashimoto, H.,Seo, H.S.,Krolak, A.,Debler, E.W. Substrate Affinity and Specificity of the ScSth1p Bromodomain Are Fine-Tuned for Versatile Histone Recognition. Structure, 27:1460-1468.e3, 2019 Cited by PubMed: 31327661 DOI: 10.1016/j.str.2019.06.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.71 Å)

Structure validation