6MMV
Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* Extracellular Domain in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4
Summary for 6MMV
Entry DOI | 10.2210/pdb6mmv/pdb |
EMDB information | 9147 9148 9149 9150 9151 9152 9153 9154 9155 9156 9157 9158 9159 9160 9161 9162 9163 9164 9165 |
Descriptor | Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2A, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | ligand-gated ion channel, nmda receptor, ionotropic glutamate receptors, membrane protein, transport protein |
Biological source | Rattus norvegicus (Rat) More |
Total number of polymer chains | 4 |
Total formula weight | 367129.13 |
Authors | Jalali-Yazdi, F.,Chowdhury, S.,Yoshioka, C.,Gouaux, E. (deposition date: 2018-10-01, release date: 2018-11-28, Last modification date: 2020-07-29) |
Primary citation | Jalali-Yazdi, F.,Chowdhury, S.,Yoshioka, C.,Gouaux, E. Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor. Cell, 175:1520-1532.e15, 2018 Cited by PubMed: 30500536DOI: 10.1016/j.cell.2018.10.043 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.71 Å) |
Structure validation
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