6MIS

Native ananain in complex with E-64

Summary for 6MIS

Entry DOI	10.2210/pdb6mis/pdb
Descriptor	Ananain, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE (3 entities in total)
Functional Keywords	pineapple cysteine protease e-64 inhibitor complex, plant protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Ananas comosus (Pineapple)
Total number of polymer chains	2
Total formula weight	47451.85
Authors	Yongqing, T.,Wilmann, P.G.,Pike, R.N.,Wijeyewickrema, L.C. (deposition date: 2018-09-20, release date: 2018-10-03, Last modification date: 2023-10-11)
Primary citation	Yongqing, T.,Wilmann, P.G.,Pan, J.,West, M.L.,Brown, T.J.,Mynott, T.,Pike, R.N.,Wijeyewickrema, L.C. Determination of the crystal structure and substrate specificity of ananain. Biochimie, 166:194-202, 2019 Cited by PubMed: 31306685 DOI: 10.1016/j.biochi.2019.07.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.98 Å)

Structure validation