6MIS
Native ananain in complex with E-64
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue E64 A 301 |
| Chain | Residue |
| A | GLN19 |
| A | ALA132 |
| A | ASN156 |
| A | HIS157 |
| B | ARG154 |
| A | GLY23 |
| A | SER24 |
| A | CYS25 |
| A | TRP26 |
| A | TYR60 |
| A | LYS63 |
| A | GLY64 |
| A | GLY65 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide E64 B 301 and CYS B 25 |
| Chain | Residue |
| B | GLN19 |
| B | GLY23 |
| B | SER24 |
| B | TRP26 |
| B | ALA27 |
| B | PHE28 |
| B | ALA29 |
| B | TYR60 |
| B | LYS63 |
| B | GLY64 |
| B | GLY65 |
| B | ALA132 |
| B | ASN156 |
| B | HIS157 |
| B | ALA158 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGrCGSCWAfAS |
| Chain | Residue | Details |
| A | GLN19-SER30 |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. LNHAIVIIGYG |
| Chain | Residue | Details |
| A | LEU155-GLY165 |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. FWIvRNSWgagWGegGYIrL |
| Chain | Residue | Details |
| A | PHE173-LEU192 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10088","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"31306685","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10089","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"31306685","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10090","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"31306685","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6MIS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6YCC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
