6MFX
Crystal structure of a 4-domain construct of a mutant of LgrA in the substrate donation state
Summary for 6MFX
Entry DOI | 10.2210/pdb6mfx/pdb |
Descriptor | Linear gramicidin synthase subunit A, N-[2-(acetylamino)ethyl]-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... (5 entities in total) |
Functional Keywords | nonribosomal peptide synthetase, tailoring domain, nrps, enzyme, natural product, linear gramicidin, ligase |
Biological source | Brevibacillus parabrevis |
Total number of polymer chains | 1 |
Total formula weight | 138960.85 |
Authors | Reimer, J.M.,Eivaskhani, M.,Schmeing, T.M. (deposition date: 2018-09-12, release date: 2019-11-20, Last modification date: 2023-10-11) |
Primary citation | Reimer, J.M.,Eivaskhani, M.,Harb, I.,Guarne, A.,Weigt, M.,Schmeing, T.M. Structures of a dimodular nonribosomal peptide synthetase reveal conformational flexibility. Science, 366:-, 2019 Cited by PubMed: 31699907DOI: 10.1126/science.aaw4388 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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