6MFF

HLA-DQ2-glia-omega1

Summary for 6MFF

• Entry DOI: 10.2210/pdb6mff/pdb
• Descriptor: HLA class II histocompatibility antigen, DQ alpha 1 chain, MHC class II HLA-DQ-beta-1 - DQ2-glia-omega1 chimeric protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: immune complex, celiac disease, gliadin epitope, tcr cross-reactivity, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 47657.97

Authors

Petersen, J.,Ciacchi, L.,Rossjohn, J. (deposition date: 2018-09-10, release date: 2018-11-21, Last modification date: 2020-07-29)

• Primary citation: Dahal-Koirala, S.,Ciacchi, L.,Petersen, J.,Risnes, L.F.,Neumann, R.S.,Christophersen, A.,Lundin, K.E.A.,Reid, H.H.,Qiao, S.W.,Rossjohn, J.,Sollid, L.M.; Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes.; J. Biol. Chem., 294:941-952, 2019; PubMed: 30455354; DOI: 10.1074/jbc.RA118.005736

Experimental method

X-RAY DIFFRACTION (2.6 Å)