6MEV

Structure of JMJD6 bound to Mono-Methyl Arginine.

Summary for 6MEV

• Entry DOI: 10.2210/pdb6mev/pdb
• Descriptor: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, 2-OXOGLUTARIC ACID, FE (III) ION, ... (5 entities in total)
• Functional Keywords: jumonji, arginine, transcription, methyl, endopeptidase, exopeptidase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 8
• Total formula weight: 322923.49

Authors

Lee, S.,Zhang, G. (deposition date: 2018-09-07, release date: 2019-09-18, Last modification date: 2020-04-01)

• Primary citation: Lee, S.,Liu, H.,Hill, R.,Chen, C.,Hong, X.,Crawford, F.,Kingsley, M.,Zhang, Q.,Liu, X.,Chen, Z.,Lengeling, A.,Bernt, K.M.,Marrack, P.,Kappler, J.,Zhou, Q.,Li, C.Y.,Xue, Y.,Hansen, K.,Zhang, G.; JMJD6 cleaves MePCE to release positive transcription elongation factor b (P-TEFb) in higher eukaryotes.; Elife, 9:-, 2020; PubMed: 32048991; DOI: 10.7554/eLife.53930

Experimental method

X-RAY DIFFRACTION (2.6 Å)