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6MCT

A designed pentameric membrane protein stabilized by van der Waals interaction

Summary for 6MCT
Entry DOI10.2210/pdb6mct/pdb
Descriptormini-eVgL membrane protein, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, SULFATE ION, ... (4 entities in total)
Functional Keywordsmembrane protein, protein design, de novo protein
Biological sourcesynthetic construct
Total number of polymer chains15
Total formula weight51104.52
Authors
Mravic, M.,Liu, L.,Degrado, W.F. (deposition date: 2018-09-02, release date: 2019-04-03, Last modification date: 2024-04-03)
Primary citationMravic, M.,Thomaston, J.L.,Tucker, M.,Solomon, P.E.,Liu, L.,DeGrado, W.F.
Packing of apolar side chains enables accurate design of highly stable membrane proteins.
Science, 363:1418-1423, 2019
Cited by
PubMed: 30923216
DOI: 10.1126/science.aav7541
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation

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