6M6D

Structure of HPPD complexed with a synthesized inhibitor

6M6D の概要

• エントリーDOI: 10.2210/pdb6m6d/pdb
• 分子名称: 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(3-trimethylsilylprop-2-ynyl)quinazoline-2,4-dione, ... (4 entities in total)
• 機能のキーワード: inhibitor, complex, oxidoreductase
• 由来する生物種: Arabidopsis thaliana (Mouse-ear cress)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 49371.31

構造登録者

Lin, H.-Y.,Yang, W.-C.,Yang, G.-F. (登録日: 2020-03-14, 公開日: 2021-03-10, 最終更新日: 2023-11-29)

• 主引用文献: Qu, R.Y.,Nan, J.X.,Yan, Y.C.,Chen, Q.,Ndikuryayo, F.,Wei, X.F.,Yang, W.C.,Lin, H.Y.,Yang, G.F.; Structure-Guided Discovery of Silicon-Containing Subnanomolar Inhibitor of Hydroxyphenylpyruvate Dioxygenase as a Potential Herbicide.; J.Agric.Food Chem., 69:459-473, 2021; PubMed: 33395281; DOI: 10.1021/acs.jafc.0c03844

実験手法

X-RAY DIFFRACTION (1.842 Å)