6LKD
in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor
Summary for 6LKD
Entry DOI | 10.2210/pdb6lkd/pdb |
Descriptor | Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, 5-[5-(4-chloranyl-3-fluoranyl-phenyl)-4-methyl-pyrazol-1-yl]-2-phenylmethoxy-benzoic acid, ... (6 entities in total) |
Functional Keywords | single pass transmembrane, kmo, hydroxygenase, flavoprotein, membrane protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 2 |
Total formula weight | 115546.32 |
Authors | Mimasu, S.,Yamagishi, H.,Kiyohara, M.,Kakefuda, K.,Okuda, T. (deposition date: 2019-12-19, release date: 2020-12-23, Last modification date: 2023-11-22) |
Primary citation | Mimasu, S.,Yamagishi, H.,Kubo, S.,Kiyohara, M.,Matsuda, T.,Yahata, T.,Thomson, H.A.,Hupp, C.D.,Liu, J.,Okuda, T.,Kakefuda, K. Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition. Commun Biol, 4:159-159, 2021 Cited by PubMed: 33542467DOI: 10.1038/s42003-021-01666-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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