6LKD

in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor

6LKD の概要

• エントリーDOI: 10.2210/pdb6lkd/pdb
• 分子名称: Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, 5-[5-(4-chloranyl-3-fluoranyl-phenyl)-4-methyl-pyrazol-1-yl]-2-phenylmethoxy-benzoic acid, ... (6 entities in total)
• 機能のキーワード: single pass transmembrane, kmo, hydroxygenase, flavoprotein, membrane protein
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 115546.32

構造登録者

Mimasu, S.,Yamagishi, H.,Kiyohara, M.,Kakefuda, K.,Okuda, T. (登録日: 2019-12-19, 公開日: 2020-12-23, 最終更新日: 2023-11-22)

• 主引用文献: Mimasu, S.,Yamagishi, H.,Kubo, S.,Kiyohara, M.,Matsuda, T.,Yahata, T.,Thomson, H.A.,Hupp, C.D.,Liu, J.,Okuda, T.,Kakefuda, K.; Full-length in meso structure and mechanism of rat kynurenine 3-monooxygenase inhibition.; Commun Biol, 4:159-159, 2021; PubMed: 33542467; DOI: 10.1038/s42003-021-01666-5

実験手法

X-RAY DIFFRACTION (3 Å)