6LFM

Cryo-EM structure of a class A GPCR

Summary for 6LFM

• Entry DOI: 10.2210/pdb6lfm/pdb
• EMDB information: 0877
• Descriptor: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• Functional Keywords: g protein coupled-receptor, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 7
• Total formula weight: 171963.89

Authors

Liu, Z.J.,Hua, T.,Liu, K.W.,Wu, L.J. (deposition date: 2019-12-03, release date: 2020-09-02, Last modification date: 2020-09-16)

• Primary citation: Liu, K.,Wu, L.,Yuan, S.,Wu, M.,Xu, Y.,Sun, Q.,Li, S.,Zhao, S.,Hua, T.,Liu, Z.J.; Structural basis of CXC chemokine receptor 2 activation and signalling.; Nature, 585:135-140, 2020; PubMed: 32610344; DOI: 10.1038/s41586-020-2492-5

Experimental method

ELECTRON MICROSCOPY (3.5 Å)