6LFL

Crystal structure of a class A GPCR

Summary for 6LFL

• Entry DOI: 10.2210/pdb6lfl/pdb
• Descriptor: C-X-C chemokine receptor type 2,GlgA glycogen synthase,C-X-C chemokine receptor type 2, 4-[[3,4-bis(oxidanylidene)-2-[[(1~{R})-1-(4-propan-2-ylfuran-2-yl)propyl]amino]cyclobuten-1-yl]amino]-~{N},~{N}-dimethyl-3-oxidanyl-pyridine-2-carboxamide (2 entities in total)
• Functional Keywords: g protein-coupled receptor, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 57121.34

Authors

Liu, Z.J.,Hua, T.,Liu, K.W.,Wu, L.J. (deposition date: 2019-12-03, release date: 2020-09-02, Last modification date: 2023-11-22)

• Primary citation: Liu, K.,Wu, L.,Yuan, S.,Wu, M.,Xu, Y.,Sun, Q.,Li, S.,Zhao, S.,Hua, T.,Liu, Z.J.; Structural basis of CXC chemokine receptor 2 activation and signalling.; Nature, 585:135-140, 2020; PubMed: 32610344; DOI: 10.1038/s41586-020-2492-5

Experimental method

X-RAY DIFFRACTION (3.2 Å)