6LC9

Crystal structure of AmpC Ent385 complex form with ceftazidime

Summary for 6LC9

• Entry DOI: 10.2210/pdb6lc9/pdb
• Descriptor: Beta-lactamase, ACYLATED CEFTAZIDIME, GLYCEROL, ... (6 entities in total)
• Functional Keywords: beta-lactamase, class c, ampc, ceftazidime, hydrolase
• Biological source: Enterobacter cloacae
• Total number of polymer chains: 2
• Total formula weight: 80852.24

Authors

Kawai, A.,Doi, Y. (deposition date: 2019-11-18, release date: 2020-04-22, Last modification date: 2022-03-23)

• Primary citation: Kawai, A.,McElheny, C.L.,Iovleva, A.,Kline, E.G.,Sluis-Cremer, N.,Shields, R.K.,Doi, Y.; Structural Basis of Reduced Susceptibility to Ceftazidime-Avibactam and Cefiderocol inEnterobacter cloacaeDue to AmpC R2 Loop Deletion.; Antimicrob.Agents Chemother., 64:-, 2020; PubMed: 32284381; DOI: 10.1128/AAC.00198-20

Experimental method

X-RAY DIFFRACTION (1.65 Å)