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6LC8

Crystal structure of AmpC Ent385 complex form with avibactam

Summary for 6LC8
Entry DOI10.2210/pdb6lc8/pdb
Related6LC7
DescriptorBeta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, SULFATE ION, ... (5 entities in total)
Functional Keywordsbeta-lactamase, class c, ampc, avibactam, hydrolase
Biological sourceEnterobacter cloacae
Total number of polymer chains2
Total formula weight80832.01
Authors
Kawai, A.,Doi, Y. (deposition date: 2019-11-18, release date: 2020-04-22, Last modification date: 2022-03-23)
Primary citationKawai, A.,McElheny, C.L.,Iovleva, A.,Kline, E.G.,Sluis-Cremer, N.,Shields, R.K.,Doi, Y.
Structural Basis of Reduced Susceptibility to Ceftazidime-Avibactam and Cefiderocol inEnterobacter cloacaeDue to AmpC R2 Loop Deletion.
Antimicrob.Agents Chemother., 64:-, 2020
Cited by
PubMed: 32284381
DOI: 10.1128/AAC.00198-20
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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