6LAE
Crystal structure of the DNA-binding domain of human XPA in complex with DNA
Summary for 6LAE
Entry DOI | 10.2210/pdb6lae/pdb |
Descriptor | DNA repair protein complementing XP-A cells, DNA (5'-D(P*GP*CP*AP*TP*CP*TP*CP*GP*CP*CP*T)-3'), DNA (5'-D(P*TP*GP*GP*CP*GP*AP*GP*AP*TP*GP*C)-3'), ... (5 entities in total) |
Functional Keywords | protein-dna complex, nucleotide excision repair, dna repair, dna binding protein, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 41776.54 |
Authors | Lian, F.M.,Yang, X.,Jiang, Y.L.,Yang, F.,Li, C.,Yang, W.,Qian, C. (deposition date: 2019-11-12, release date: 2020-02-26, Last modification date: 2023-11-22) |
Primary citation | Lian, F.M.,Yang, X.,Jiang, Y.L.,Yang, F.,Li, C.,Yang, W.,Qian, C. New structural insights into the recognition of undamaged splayed-arm DNA with a single pair of non-complementary nucleotides by human nucleotide excision repair protein XPA. Int.J.Biol.Macromol., 148:466-474, 2020 Cited by PubMed: 31962067DOI: 10.1016/j.ijbiomac.2020.01.169 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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