6LAE

Crystal structure of the DNA-binding domain of human XPA in complex with DNA

6LAE の概要

• エントリーDOI: 10.2210/pdb6lae/pdb
• 分子名称: DNA repair protein complementing XP-A cells, DNA (5'-D(P*GP*CP*AP*TP*CP*TP*CP*GP*CP*CP*T)-3'), DNA (5'-D(P*TP*GP*GP*CP*GP*AP*GP*AP*TP*GP*C)-3'), ... (5 entities in total)
• 機能のキーワード: protein-dna complex, nucleotide excision repair, dna repair, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 41776.54

構造登録者

Lian, F.M.,Yang, X.,Jiang, Y.L.,Yang, F.,Li, C.,Yang, W.,Qian, C. (登録日: 2019-11-12, 公開日: 2020-02-26, 最終更新日: 2023-11-22)

• 主引用文献: Lian, F.M.,Yang, X.,Jiang, Y.L.,Yang, F.,Li, C.,Yang, W.,Qian, C.; New structural insights into the recognition of undamaged splayed-arm DNA with a single pair of non-complementary nucleotides by human nucleotide excision repair protein XPA.; Int.J.Biol.Macromol., 148:466-474, 2020; PubMed: 31962067; DOI: 10.1016/j.ijbiomac.2020.01.169

実験手法

X-RAY DIFFRACTION (2.81 Å)