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6KYK

Crystal structure of Shank3 NTD-ANK mutant in complex with Rap1

Summary for 6KYK
Entry DOI10.2210/pdb6kyk/pdb
Related6KYH
DescriptorSH3 and multiple ankyrin repeat domains protein 3, Ras-related protein Rap-1b, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (5 entities in total)
Functional Keywordsshank3, gtpase, synaptic scaffold protein, structural protein-signaling protein complex, structural protein/signaling protein
Biological sourceMus musculus (Mouse)
More
Total number of polymer chains6
Total formula weight162226.76
Authors
Cai, Q.,Zhang, M. (deposition date: 2019-09-19, release date: 2019-12-04, Last modification date: 2023-11-22)
Primary citationCai, Q.,Hosokawa, T.,Zeng, M.,Hayashi, Y.,Zhang, M.
Shank3 Binds to and Stabilizes the Active Form of Rap1 and HRas GTPases via Its NTD-ANK Tandem with Distinct Mechanisms.
Structure, 28:290-, 2020
Cited by
PubMed: 31879129
DOI: 10.1016/j.str.2019.11.018
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.82 Å)
Structure validation

221051

數據於2024-06-12公開中

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