6KYK
Crystal structure of Shank3 NTD-ANK mutant in complex with Rap1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | SH3 and multiple ankyrin repeat domains protein 3 | polymer | 374 | 41394.7 | 2 | UniProt (Q4ACU6) Pfam (PF12796) In PDB | Mus musculus (Mouse) | Shank3,Proline-rich synapse-associated protein 2,ProSAP2,SPANK-2 |
2 | C, D, E, F | Ras-related protein Rap-1b | polymer | 170 | 19312.8 | 4 | UniProt (P61224) Pfam (PF00071) In PDB | Homo sapiens (Human) | GTP-binding protein smg p21B |
3 | C, D, E, F | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 4 | Chemie (GNP) | |||
4 | C, D, E, F | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
5 | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 368 (UniProt: Q4ACU6)
C, D, E, F: 1 - 167 (UniProt: P61224)
PDB | External Database | Details |
---|---|---|
Gly -5 | - | expression tag |
Pro -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Glu -1 | - | expression tag |
Phe 0 | - | expression tag |
Arg 231 | Leu 231 | engineered mutation |
Tyr 304 | Phe 304 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 160040.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 2186.0 | |
All* | Total formula weight | 162226.8 |