6KYH

Crystal structure of Shank3 NTD-ANK A42K mutant in complex with HRas

6KYH の概要

• エントリーDOI: 10.2210/pdb6kyh/pdb
• 分子名称: SH3 and multiple ankyrin repeat domains protein 3, GTPase HRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (4 entities in total)
• 機能のキーワード: shank3, gtpase, synaptic scaffold protein, structural protein-signaling protein complex, structural protein/signaling protein
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 240414.66

構造登録者

Cai, Q.,Zhang, M. (登録日: 2019-09-18, 公開日: 2019-12-04, 最終更新日: 2023-11-22)

• 主引用文献: Cai, Q.,Hosokawa, T.,Zeng, M.,Hayashi, Y.,Zhang, M.; Shank3 Binds to and Stabilizes the Active Form of Rap1 and HRas GTPases via Its NTD-ANK Tandem with Distinct Mechanisms.; Structure, 28:290-, 2020; PubMed: 31879129; DOI: 10.1016/j.str.2019.11.018

実験手法

X-RAY DIFFRACTION (3.3 Å)