6KWX
cryo-EM structure of human PA200
Summary for 6KWX
Entry DOI | 10.2210/pdb6kwx/pdb |
EMDB information | 0780 |
Descriptor | Proteasome activator complex subunit 4, [(1~{S},2~{R},3~{R},4~{S},5~{S},6~{R})-2-[oxidanyl(phosphonooxy)phosphoryl]oxy-3,4,5,6-tetraphosphonooxy-cyclohexyl] phosphono hydrogen phosphate, INOSITOL HEXAKISPHOSPHATE (3 entities in total) |
Functional Keywords | proteasome activator, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 217254.90 |
Authors | Ouyang, S.,Hongxin, G. (deposition date: 2019-09-09, release date: 2020-04-01, Last modification date: 2024-03-27) |
Primary citation | Guan, H.,Wang, Y.,Yu, T.,Huang, Y.,Li, M.,Saeed, A.F.U.H.,Perculija, V.,Li, D.,Xiao, J.,Wang, D.,Zhu, P.,Ouyang, S. Cryo-EM structures of the human PA200 and PA200-20S complex reveal regulation of proteasome gate opening and two PA200 apertures. Plos Biol., 18:e3000654-e3000654, 2020 Cited by PubMed: 32134919DOI: 10.1371/journal.pbio.3000654 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.75 Å) |
Structure validation
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