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6KTR

Crystal structure of fibroblast growth factor 19 in complex with Fab

Summary for 6KTR
Entry DOI10.2210/pdb6ktr/pdb
DescriptorG1A8-Fab-HC, G1A8-Fab-LC, Fibroblast growth factor 19, ... (6 entities in total)
Functional Keywordscomplex, growth factor, antibody, cell cycle, immune system-protein binding complex, immune system/protein binding
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains6
Total formula weight145328.46
Authors
Liu, H.,Zheng, S.,Hou, X.,Liu, X.,Lv, X.,Li, Y.,Li, W.,Sui, J. (deposition date: 2019-08-28, release date: 2020-07-08, Last modification date: 2023-11-22)
Primary citationLiu, H.,Zheng, S.,Hou, X.,Liu, X.,Du, K.,Lv, X.,Li, Y.,Yang, F.,Li, W.,Sui, J.
Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects.
Cancer Sci., 111:1750-1760, 2020
Cited by
PubMed: 32061104
DOI: 10.1111/cas.14353
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.59775753879 Å)
Structure validation

217705

數據於2024-03-27公開中

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