6KTR

Crystal structure of fibroblast growth factor 19 in complex with Fab

6KTR の概要

• エントリーDOI: 10.2210/pdb6ktr/pdb
• 分子名称: G1A8-Fab-HC, G1A8-Fab-LC, Fibroblast growth factor 19, ... (6 entities in total)
• 機能のキーワード: complex, growth factor, antibody, cell cycle, immune system-protein binding complex, immune system/protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 145328.46

構造登録者

Liu, H.,Zheng, S.,Hou, X.,Liu, X.,Lv, X.,Li, Y.,Li, W.,Sui, J. (登録日: 2019-08-28, 公開日: 2020-07-08, 最終更新日: 2023-11-22)

• 主引用文献: Liu, H.,Zheng, S.,Hou, X.,Liu, X.,Du, K.,Lv, X.,Li, Y.,Yang, F.,Li, W.,Sui, J.; Novel Abs targeting the N-terminus of fibroblast growth factor 19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects.; Cancer Sci., 111:1750-1760, 2020; PubMed: 32061104; DOI: 10.1111/cas.14353

実験手法

X-RAY DIFFRACTION (2.59775753879 Å)