6KNM
Apelin receptor in complex with single domain antibody
Summary for 6KNM
Entry DOI | 10.2210/pdb6knm/pdb |
Descriptor | Apelin receptor,Rubredoxin,Apelin receptor, Single domain antibody JN241, ZINC ION (3 entities in total) |
Functional Keywords | gpcr, single-domain antibody, antagonist, agonist, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 60275.35 |
Authors | |
Primary citation | Ma, Y.,Ding, Y.,Song, X.,Ma, X.,Li, X.,Zhang, N.,Song, Y.,Sun, Y.,Shen, Y.,Zhong, W.,Hu, L.A.,Ma, Y.,Zhang, M.Y. Structure-guided discovery of a single-domain antibody agonist against human apelin receptor. Sci Adv, 6:eaax7379-eaax7379, 2020 Cited by PubMed: 31998837DOI: 10.1126/sciadv.aax7379 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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