6KC6

HOIP-HOIPIN8 complex

Summary for 6KC6

Entry DOI	10.2210/pdb6kc6/pdb
Descriptor	E3 ubiquitin-protein ligase RNF31, ZINC ION, 2-[3-[2,6-bis(fluoranyl)-4-(1~{H}-pyrazol-4-yl)phenyl]-3-oxidanylidene-propyl]-4-(1-methylpyrazol-4-yl)benzoic acid, ... (6 entities in total)
Functional Keywords	ubiquitin, e3, inhibitor complex, ligase
Biological source	Homo sapiens (Human)
Total number of polymer chains	6
Total formula weight	157642.32
Authors	Sato, Y.,Fukai, S. (deposition date: 2019-06-27, release date: 2020-04-15, Last modification date: 2023-11-22)
Primary citation	Oikawa, D.,Sato, Y.,Ohtake, F.,Komakura, K.,Hanada, K.,Sugawara, K.,Terawaki, S.,Mizukami, Y.,Phuong, H.T.,Iio, K.,Obika, S.,Fukushi, M.,Irie, T.,Tsuruta, D.,Sakamoto, S.,Tanaka, K.,Saeki, Y.,Fukai, S.,Tokunaga, F. Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses. Commun Biol, 3:163-163, 2020 Cited by PubMed: 32246052 DOI: 10.1038/s42003-020-0882-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.123 Å)

Structure validation