Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0071797 | cellular_component | LUBAC complex |
| C | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0071797 | cellular_component | LUBAC complex |
| E | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| E | 0008270 | molecular_function | zinc ion binding |
| E | 0071797 | cellular_component | LUBAC complex |
| G | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| G | 0008270 | molecular_function | zinc ion binding |
| G | 0071797 | cellular_component | LUBAC complex |
| I | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| I | 0008270 | molecular_function | zinc ion binding |
| I | 0071797 | cellular_component | LUBAC complex |
| K | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| K | 0008270 | molecular_function | zinc ion binding |
| K | 0071797 | cellular_component | LUBAC complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1101 |
| Chain | Residue |
| A | CYS871 |
| A | CYS874 |
| A | CYS890 |
| A | CYS893 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1102 |
| Chain | Residue |
| A | CYS898 |
| A | CYS901 |
| A | HIS926 |
| A | CYS930 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1103 |
| Chain | Residue |
| A | CYS916 |
| A | HIS923 |
| A | HIS925 |
| A | CYS911 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 1104 |
| Chain | Residue |
| A | CYS969 |
| A | CYS986 |
| A | CYS998 |
| A | HIS1001 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue D60 A 1105 |
| Chain | Residue |
| A | GLY884 |
| A | CYS885 |
| A | MET886 |
| A | HIS887 |
| A | LEU922 |
| A | PHE932 |
| A | ARG935 |
| A | ASP936 |
| A | HOH1210 |
| I | D601105 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 1106 |
| Chain | Residue |
| A | TYR1021 |
| A | ARG1032 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 1107 |
| Chain | Residue |
| A | ASN903 |
| A | GLN1065 |
| C | LEU1041 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 1108 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 1109 |
| Chain | Residue |
| A | GLY884 |
| A | ARG935 |
| A | ALA1000 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 1110 |
| Chain | Residue |
| A | LEU1009 |
| A | HIS1013 |
| A | ARG1070 |
| A | HOH1202 |
| I | GLN947 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 1101 |
| Chain | Residue |
| C | CYS871 |
| C | CYS874 |
| C | CYS890 |
| C | CYS893 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 1102 |
| Chain | Residue |
| C | CYS898 |
| C | CYS901 |
| C | HIS926 |
| C | CYS930 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 1103 |
| Chain | Residue |
| C | CYS911 |
| C | CYS916 |
| C | HIS923 |
| C | HIS925 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 1104 |
| Chain | Residue |
| C | CYS969 |
| C | CYS986 |
| C | CYS998 |
| C | HIS1001 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 1106 |
| Chain | Residue |
| C | TYR1021 |
| C | ARG1032 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 1107 |
| Chain | Residue |
| C | GLY884 |
| C | ARG935 |
| C | ALA1000 |
| C | GLU1004 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 1108 |
| Chain | Residue |
| C | GLY883 |
| C | LYS988 |
| C | HOH1226 |
| K | D601105 |
| K | HOH1203 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 1109 |
| Chain | Residue |
| C | ASN954 |
| C | ARG970 |
| C | TYR1005 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 1101 |
| Chain | Residue |
| E | CYS871 |
| E | CYS874 |
| E | CYS890 |
| E | CYS893 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 1102 |
| Chain | Residue |
| E | CYS898 |
| E | CYS901 |
| E | HIS926 |
| E | CYS930 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 1103 |
| Chain | Residue |
| E | CYS911 |
| E | CYS916 |
| E | HIS923 |
| E | HIS925 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN E 1104 |
| Chain | Residue |
| E | CYS969 |
| E | CYS986 |
| E | CYS998 |
| E | HIS1001 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue CL E 1106 |
| Chain | Residue |
| E | TYR1021 |
| E | ALA1029 |
| E | ARG1032 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL E 1107 |
| Chain | Residue |
| E | GLY884 |
| E | ARG935 |
| E | ALA1000 |
| E | GLU1004 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL E 1108 |
| Chain | Residue |
| E | LEU922 |
| E | LYS988 |
| E | D601105 |
| E | HOH1209 |
| site_id | AE8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN G 1101 |
| Chain | Residue |
| G | CYS890 |
| G | CYS893 |
| G | CYS871 |
| G | CYS874 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN G 1102 |
| Chain | Residue |
| G | CYS898 |
| G | CYS901 |
| G | HIS926 |
| G | CYS930 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN G 1103 |
| Chain | Residue |
| G | CYS911 |
| G | CYS916 |
| G | HIS923 |
| G | HIS925 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN G 1104 |
| Chain | Residue |
| G | CYS969 |
| G | CYS986 |
| G | CYS998 |
| G | HIS1001 |
| site_id | AF3 |
| Number of Residues | 2 |
| Details | binding site for residue CL G 1106 |
| Chain | Residue |
| G | TYR1021 |
| G | ARG1032 |
| site_id | AF4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL G 1107 |
| Chain | Residue |
| G | GLY884 |
| G | ARG935 |
| G | ALA1000 |
| G | GLU1004 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN I 1101 |
| Chain | Residue |
| I | CYS871 |
| I | CYS874 |
| I | CYS890 |
| I | CYS893 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN I 1102 |
| Chain | Residue |
| I | CYS898 |
| I | CYS901 |
| I | HIS926 |
| I | CYS930 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN I 1103 |
| Chain | Residue |
| I | CYS911 |
| I | CYS916 |
| I | HIS923 |
| I | HIS925 |
| site_id | AF8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN I 1104 |
| Chain | Residue |
| I | CYS969 |
| I | CYS986 |
| I | CYS998 |
| I | HIS1001 |
| site_id | AF9 |
| Number of Residues | 2 |
| Details | binding site for residue CL I 1106 |
| Chain | Residue |
| I | TYR1021 |
| I | ARG1032 |
| site_id | AG1 |
| Number of Residues | 1 |
| Details | binding site for residue CL I 1107 |
| site_id | AG2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN K 1101 |
| Chain | Residue |
| K | CYS871 |
| K | CYS874 |
| K | CYS890 |
| K | CYS893 |
| site_id | AG3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN K 1102 |
| Chain | Residue |
| K | CYS898 |
| K | CYS901 |
| K | HIS926 |
| K | CYS930 |
| site_id | AG4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN K 1103 |
| Chain | Residue |
| K | CYS911 |
| K | CYS916 |
| K | HIS923 |
| K | HIS925 |
| site_id | AG5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN K 1104 |
| Chain | Residue |
| K | CYS969 |
| K | CYS986 |
| K | CYS998 |
| K | HIS1001 |
| site_id | AG6 |
| Number of Residues | 2 |
| Details | binding site for residue CL K 1106 |
| Chain | Residue |
| K | TYR1021 |
| K | ARG1032 |
| site_id | AG7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL K 1107 |
| Chain | Residue |
| C | LEU922 |
| C | D601105 |
| C | HOH1208 |
| K | LYS988 |
| site_id | AG8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL K 1108 |
| Chain | Residue |
| E | LYS1056 |
| E | GLU1060 |
| K | ASP870 |
| K | PRO872 |
| K | SER1066 |
| site_id | AG9 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide D60 C 1105 and CYS C 885 |
| Chain | Residue |
| C | ARG882 |
| C | GLY883 |
| C | GLY884 |
| C | MET886 |
| C | HIS887 |
| C | PHE905 |
| C | LEU922 |
| C | PHE932 |
| C | ARG935 |
| C | ASP936 |
| C | HOH1208 |
| C | HOH1211 |
| K | D601105 |
| K | GOL1107 |
| site_id | AH1 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide D60 E 1105 and CYS E 885 |
| Chain | Residue |
| E | ARG882 |
| E | GLY883 |
| E | GLY884 |
| E | MET886 |
| E | HIS887 |
| E | ARG935 |
| E | ASP936 |
| E | GOL1108 |
| site_id | AH2 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide D60 G 1105 and CYS G 885 |
| Chain | Residue |
| G | ARG882 |
| G | GLY883 |
| G | GLY884 |
| G | MET886 |
| G | HIS887 |
| G | LEU922 |
| G | ARG935 |
| G | ASP936 |
| G | HOH1206 |
| site_id | AH3 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide D60 I 1105 and CYS I 885 |
| Chain | Residue |
| A | GLY883 |
| A | D601105 |
| I | ARG882 |
| I | GLY883 |
| I | GLY884 |
| I | MET886 |
| I | HIS887 |
| I | LEU922 |
| I | ARG935 |
| I | ASP936 |
| I | HOH1209 |
| I | HOH1229 |
| site_id | AH4 |
| Number of Residues | 14 |
| Details | binding site for Di-peptide D60 K 1105 and CYS K 885 |
| Chain | Residue |
| C | GLY883 |
| C | D601105 |
| C | GOL1108 |
| K | ARG882 |
| K | GLY883 |
| K | GLY884 |
| K | MET886 |
| K | HIS887 |
| K | PHE905 |
| K | LEU922 |
| K | PHE932 |
| K | ARG935 |
| K | ASP936 |
| K | HOH1203 |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CrHqFCsgCY |
| Chain | Residue | Details |
| A | CYS893-TYR902 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | CYS871-CYS901 | |
| C | CYS871-CYS901 | |
| E | CYS871-CYS901 | |
| G | CYS871-CYS901 | |
| I | CYS871-CYS901 | |
| K | CYS871-CYS901 | |
| Chain | Residue | Details |
| A | CYS885 | |
| C | CYS885 | |
| E | CYS885 | |
| G | CYS885 | |
| I | CYS885 | |
| K | CYS885 | |
| Chain | Residue | Details |
| A | CYS871 | |
| C | CYS874 | |
| C | CYS890 | |
| C | CYS893 | |
| C | CYS898 | |
| C | CYS901 | |
| C | CYS916 | |
| C | HIS925 | |
| E | CYS871 | |
| E | CYS874 | |
| E | CYS890 | |
| A | CYS874 | |
| E | CYS893 | |
| E | CYS898 | |
| E | CYS901 | |
| E | CYS916 | |
| E | HIS925 | |
| G | CYS871 | |
| G | CYS874 | |
| G | CYS890 | |
| G | CYS893 | |
| G | CYS898 | |
| A | CYS890 | |
| G | CYS901 | |
| G | CYS916 | |
| G | HIS925 | |
| I | CYS871 | |
| I | CYS874 | |
| I | CYS890 | |
| I | CYS893 | |
| I | CYS898 | |
| I | CYS901 | |
| I | CYS916 | |
| A | CYS893 | |
| I | HIS925 | |
| K | CYS871 | |
| K | CYS874 | |
| K | CYS890 | |
| K | CYS893 | |
| K | CYS898 | |
| K | CYS901 | |
| K | CYS916 | |
| K | HIS925 | |
| A | CYS898 | |
| A | CYS901 | |
| A | CYS916 | |
| A | HIS925 | |
| C | CYS871 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | CROSSLNK: (Microbial infection) Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:27572974 |
| Chain | Residue | Details |
| A | LYS875 | |
| K | LYS875 | |
| C | LYS875 | |
| E | LYS875 | |
| G | LYS875 | |
| I | LYS875 | |
