6KC4
Crystal structure of human Fer SH2 domain bound to a phosphopeptide (DEpYENVD)
Summary for 6KC4
Entry DOI | 10.2210/pdb6kc4/pdb |
Descriptor | Tyrosine-protein kinase Fer, phosphopeptide (EDpYENVD) (3 entities in total) |
Functional Keywords | sh2 domain, signaling protein, transferase-signaling protein complex, transferase/signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 76236.90 |
Authors | Matsuura, Y. (deposition date: 2019-06-27, release date: 2019-09-04, Last modification date: 2023-11-22) |
Primary citation | Matsuura, Y. High-resolution structural analysis shows how different crystallographic environments can induce alternative modes of binding of a phosphotyrosine peptide to the SH2 domain of Fer tyrosine kinase. Protein Sci., 28:2011-2019, 2019 Cited by PubMed: 31441171DOI: 10.1002/pro.3713 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.37 Å) |
Structure validation
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