6KAG

Crystal structure of the SMARCB1/SMARCC2 subcomplex

Summary for 6KAG

Entry DOI	10.2210/pdb6kag/pdb
Descriptor	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, SWI/SNF complex subunit SMARCC2 (3 entities in total)
Functional Keywords	chromatin remodeling complex, swi-snf complex, baf complex, smarcb1and smarcc2 subcomplex, atypical teratoid/rhabdoid tumor, cell cycle
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	69300.64
Authors	Chen, G.,Zhou, H.,Giancotti, F.G.,Long, J. (deposition date: 2019-06-22, release date: 2020-09-23, Last modification date: 2024-03-27)
Primary citation	Chen, G.,Zhou, H.,Liu, B.,Wang, Y.,Zhao, J.,Giancotti, F.G.,Long, J. A heterotrimeric SMARCB1-SMARCC2 subcomplex is required for the assembly and tumor suppression function of the BAF chromatin-remodeling complex. Cell Discov, 6:66-66, 2020 Cited by PubMed: 33024572 DOI: 10.1038/s41421-020-00196-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.601 Å)

Structure validation