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6K7G

Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class1)

Summary for 6K7G
Entry DOI10.2210/pdb6k7g/pdb
EMDB information9931
DescriptorPhospholipid-transporting ATPase, Cell cycle control protein 50A, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywordsflippase, membrane protein
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight172781.06
Authors
Hiraizumi, M.,Yamashita, K.,Nishizawa, T.,Nureki, O. (deposition date: 2019-06-07, release date: 2019-08-28, Last modification date: 2021-02-10)
Primary citationHiraizumi, M.,Yamashita, K.,Nishizawa, T.,Nureki, O.
Cryo-EM structures capture the transport cycle of the P4-ATPase flippase.
Science, 365:1149-1155, 2019
Cited by
PubMed: 31416931
DOI: 10.1126/science.aay3353
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation

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