6JZ2
b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution
Summary for 6JZ2
Entry DOI | 10.2210/pdb6jz2/pdb |
Descriptor | Beta-glucuronidase, (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, ... (5 entities in total) |
Functional Keywords | b-glucuronidase, hydrolase |
Biological source | Ruminococcus gnavus |
Total number of polymer chains | 2 |
Total formula weight | 146450.79 |
Authors | Dashnyam, P.,Lin, H.Y. (deposition date: 2019-04-30, release date: 2020-06-10, Last modification date: 2023-11-22) |
Primary citation | Dashnyam, P.,Lin, H.Y.,Chen, C.Y.,Gao, S.,Yeh, L.F.,Hsieh, W.C.,Tu, Z.,Lin, C.H. Substituent Position of Iminocyclitols Determines the Potency and Selectivity for Gut Microbial Xenobiotic-Reactivating Enzymes. J.Med.Chem., 63:4617-4627, 2020 Cited by PubMed: 32105467DOI: 10.1021/acs.jmedchem.9b01918 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.29 Å) |
Structure validation
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