6JRP
Crystal structure of CIC-HMG-ETV5-DNA complex
Summary for 6JRP
Entry DOI | 10.2210/pdb6jrp/pdb |
Descriptor | Protein capicua homolog, DNA (5'-D(*AP*TP*GP*AP*AP*TP*GP*AP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*TP*CP*AP*TP*TP*CP*AP*T)-3') (3 entities in total) |
Functional Keywords | repressor, protein-dna complex, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 66334.29 |
Authors | Song, J.J.,Lee, H. (deposition date: 2019-04-05, release date: 2019-07-31, Last modification date: 2020-01-08) |
Primary citation | Lee, H.,Song, J.J. The crystal structure of Capicua HMG-box domain complexed with the ETV5-DNA and its implications for Capicua-mediated cancers. Febs J., 286:4951-4963, 2019 Cited by PubMed: 31323153DOI: 10.1111/febs.15008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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