6JMQ

LAT1-CD98hc complex bound to MEM-108 Fab

Summary for 6JMQ

• Entry DOI: 10.2210/pdb6jmq/pdb
• EMDB information: 9849
• Descriptor: Large neutral amino acids transporter small subunit 1, 4F2 cell-surface antigen heavy chain, Antibody, ... (7 entities in total)
• Functional Keywords: transporter, glycoprotein, complex, membrane protein, membrane protein-immune system complex, membrane protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 172939.68

Authors

Lee, Y.,Nishizawa, T.,Kusakizako, T.,Oda, K.,Ishitani, R.,Nakane, T.,Nureki, O. (deposition date: 2019-03-13, release date: 2019-06-19, Last modification date: 2020-07-29)

• Primary citation: Lee, Y.,Wiriyasermkul, P.,Jin, C.,Quan, L.,Ohgaki, R.,Okuda, S.,Kusakizako, T.,Nishizawa, T.,Oda, K.,Ishitani, R.,Yokoyama, T.,Nakane, T.,Shirouzu, M.,Endou, H.,Nagamori, S.,Kanai, Y.,Nureki, O.; Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc.; Nat.Struct.Mol.Biol., 26:510-517, 2019; PubMed: 31160781; DOI: 10.1038/s41594-019-0237-7

Experimental method

ELECTRON MICROSCOPY (3.31 Å)