6JIO

Human LXR-beta in complex with a ligand

Summary for 6JIO

Entry DOI	10.2210/pdb6jio/pdb
Descriptor	Oxysterols receptor LXR-beta, tert-butyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate (3 entities in total)
Functional Keywords	nuclear receptor, dna binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	125182.99
Authors	Zhang, Z.,Zhou, H. (deposition date: 2019-02-22, release date: 2019-10-16, Last modification date: 2023-11-22)
Primary citation	Zhang, Z.,Chen, H.,Chen, Z.,Ding, P.,Ju, Y.,Gu, Q.,Xu, J.,Zhou, H. Identify liver X receptor beta modulator building blocks by developing a fluorescence polarization-based competition assay. Eur.J.Med.Chem., 178:458-467, 2019 Cited by PubMed: 31202993 DOI: 10.1016/j.ejmech.2019.06.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation