6JIO
Human LXR-beta in complex with a ligand
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Oxysterols receptor LXR-beta | polymer | 274 | 31171.6 | 4 | UniProt (P55055) Pfam (PF00104) In PDB | Homo sapiens (Human) | Liver X receptor beta,Nuclear receptor NER,Nuclear receptor subfamily 1 group H member 2,Ubiquitously-expressed nuclear receptor |
2 | A, D | tert-butyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate | non-polymer | 248.3 | 2 | Chemie (BQ3) | |||
3 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 215 - 461 (UniProt: P55055)
PDB | External Database | Details |
---|---|---|
Met 207 | - | initiating methionine |
Gly 208 | - | expression tag |
His 209 | - | expression tag |
His 210 | - | expression tag |
His 211 | - | expression tag |
His 212 | - | expression tag |
His 213 | - | expression tag |
His 214 | - | expression tag |
Ala 259 | Gln 258 | engineered mutation |
Gly 261 | Arg 260 | engineered mutation |
Ser 262 | Asp 261 | engineered mutation |
Ser 264 | Arg 263 | engineered mutation |
Gly 462 | - | expression tag |
Ser 463 | - | expression tag |
Gly 464 | - | expression tag |
Ser 465 | - | expression tag |
Gly 466 | - | expression tag |
Ser 467 | - | expression tag |
His 468 | - | expression tag |
Lys 469 | - | expression tag |
Ile 470 | - | expression tag |
Leu 471 | - | expression tag |
His 472 | - | expression tag |
Arg 473 | - | expression tag |
Leu 474 | - | expression tag |
Leu 475 | - | expression tag |
Gln 476 | - | expression tag |
Asp 477 | - | expression tag |
Ser 478 | - | expression tag |
Ser 479 | - | expression tag |
Ser 480 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 124686.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 496.6 | |
All* | Total formula weight | 125183.0 |