6J8G
Structure of human voltage-gated sodium channel Nav1.7 in complex with auxiliary beta subunits, huwentoxin-IV and saxitoxin (Y1755 up)
Summary for 6J8G
Entry DOI | 10.2210/pdb6j8g/pdb |
EMDB information | 9781 |
Descriptor | Sodium channel subunit beta-2, Sodium channel protein type 9 subunit alpha, Sodium channel subunit beta-1, ... (6 entities in total) |
Functional Keywords | voltage-gated sodium channel, membrane protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 282996.44 |
Authors | |
Primary citation | Shen, H.,Liu, D.,Wu, K.,Lei, J.,Yan, N. Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins. Science, 363:1303-1308, 2019 Cited by PubMed: 30765606DOI: 10.1126/science.aaw2493 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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