6J8E

Human Nav1.2-beta2-KIIIA ternary complex

Summary for 6J8E

• Entry DOI: 10.2210/pdb6j8e/pdb
• EMDB information: 9780
• Descriptor: Sodium channel subunit beta-2, Sodium channel protein type 2 subunit alpha, Mu-conotoxin KIIIA, ... (8 entities in total)
• Functional Keywords: transmembrane protein, membrane protein, membrane protein-toxin complex, membrane protein/toxin
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 251187.00

Authors

Pan, X.,Li, Z.,Huang, X.,Huang, G.,Yan, N. (deposition date: 2019-01-18, release date: 2019-02-27, Last modification date: 2020-07-29)

• Primary citation: Pan, X.,Li, Z.,Huang, X.,Huang, G.,Gao, S.,Shen, H.,Liu, L.,Lei, J.,Yan, N.; Molecular basis for pore blockade of human Na+channel Nav1.2 by the mu-conotoxin KIIIA.; Science, 363:1309-1313, 2019; PubMed: 30765605; DOI: 10.1126/science.aaw2999

Experimental method

ELECTRON MICROSCOPY (3 Å)