6J8E
Human Nav1.2-beta2-KIIIA ternary complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | C | Sodium channel subunit beta-2 | polymer | 122 | 14267.3 | 1 | UniProt (O60939) Pfam (PF07686) In PDB | Homo sapiens (Human) | |
| 2 | A | Sodium channel protein type 2 subunit alpha | polymer | 2048 | 232800.2 | 1 | UniProt (Q99250) Pfam (PF00520) Pfam (PF11933) Pfam (PF06512) In PDB | Homo sapiens (Human) | HBSC II,Sodium channel protein brain II subunit alpha,Sodium channel protein type II subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.2 |
| 3 | D | Mu-conotoxin KIIIA | polymer | 16 | 1895.2 | 1 | UniProt (P0C195) In PDB | Conus kinoshitai | |
| 4 | B | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | A | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en | non-polymer | 544.8 | 1 | Chemie (9Z9) | |||
| 8 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) |
Sequence modifications
A: 1 - 2005 (UniProt: Q99250)
| PDB | External Database | Details |
|---|---|---|
| Met -42 | - | expression tag |
| Ala -41 | - | expression tag |
| Ser -40 | - | expression tag |
| Trp -39 | - | expression tag |
| Ser -38 | - | expression tag |
| His -37 | - | expression tag |
| Pro -36 | - | expression tag |
| Gln -35 | - | expression tag |
| Phe -34 | - | expression tag |
| Glu -33 | - | expression tag |
| Lys -32 | - | expression tag |
| Gly -31 | - | expression tag |
| Gly -30 | - | expression tag |
| Gly -29 | - | expression tag |
| Ala -28 | - | expression tag |
| Arg -27 | - | expression tag |
| Gly -26 | - | expression tag |
| Gly -25 | - | expression tag |
| Ser -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Gly -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Ser -20 | - | expression tag |
| Trp -19 | - | expression tag |
| Ser -18 | - | expression tag |
| His -17 | - | expression tag |
| Pro -16 | - | expression tag |
| Gln -15 | - | expression tag |
| Phe -14 | - | expression tag |
| Glu -13 | - | expression tag |
| Lys -12 | - | expression tag |
| Gly -11 | - | expression tag |
| Phe -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Tyr -8 | - | expression tag |
| Lys -7 | - | expression tag |
| Asp -6 | - | expression tag |
| Asp -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Lys -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Thr 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 248962.7 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1435.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 789.0 | |
| All* | Total formula weight | 251187.0 |
