6IY9
Crystal structure of aminoglycoside 7"-phoshotransferase-Ia (APH(7")-Ia/HYG) from Streptomyces hygroscopicus complexed with hygromycin B
Summary for 6IY9
Entry DOI | 10.2210/pdb6iy9/pdb |
Descriptor | Hygromycin-B 7''-O-kinase, HYGROMYCIN B VARIANT, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... (5 entities in total) |
Functional Keywords | kinase, complex, transferase |
Biological source | Streptomyces hygroscopicus |
Total number of polymer chains | 2 |
Total formula weight | 78432.47 |
Authors | Takenoya, M.,Shimamura, T.,Yamanaka, R.,Adachi, Y.,Ito, S.,Sasaki, Y.,Nakamura, A.,Yajima, S. (deposition date: 2018-12-14, release date: 2019-09-11, Last modification date: 2019-11-20) |
Primary citation | Takenoya, M.,Shimamura, T.,Yamanaka, R.,Adachi, Y.,Ito, S.,Sasaki, Y.,Nakamura, A.,Yajima, S. Structural basis for the substrate recognition of aminoglycoside 7''-phosphotransferase-Ia from Streptomyces hygroscopicus. Acta Crystallogr.,Sect.F, 75:599-607, 2019 Cited by PubMed: 31475927DOI: 10.1107/S2053230X19011105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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