6IY6

Crystal structure of human cytosolic aspartyl-tRNA synthetase (DRS) in complex with glutathion-S transferase (GST) domains from Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) and glutamyl-prolyl-tRNA synthetase (EPRS)

6IY6 の概要

• エントリーDOI: 10.2210/pdb6iy6/pdb
• 分子名称: Aspartate--tRNA ligase, cytoplasmic, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2, Bifunctional glutamate/proline--tRNA ligase, ... (6 entities in total)
• 機能のキーワード: aminoacyl-trna transferase glutathion-s transferase domain, translation
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 401385.13

構造登録者

Park, S.H.,Hahn, H.,Han, B.W. (登録日: 2018-12-13, 公開日: 2019-09-11, 最終更新日: 2023-11-22)

• 主引用文献: Hahn, H.,Park, S.H.,Kim, H.J.,Kim, S.,Han, B.W.; The DRS-AIMP2-EPRS subcomplex acts as a pivot in the multi-tRNA synthetase complex.; Iucrj, 6:958-967, 2019; PubMed: 31576228; DOI: 10.1107/S2052252519010790

実験手法

X-RAY DIFFRACTION (3.6 Å)